There are a variety of disease states
(Cancer, AIDS, Cardiac diseases) where systemic drug administration has poor
efficacy due to low solubility, random body distribution and toxicity problems.
Therefore, drug entrapped in polymeric beads offer novel drug delivery approach
for an intended application, such as targeted locations and long-term delivery
times (days, weeks, months, and even years). Multiparticulate drug delivery
systems have various well known advantages over single unit dosage forms. The
potential use of microspheres in pharmaceutical industry has been considered
since the 1960s for the following applications.
• Taste and odor masking
• Conversion of oils and other liquids to
solids for the ease of handling
• Protection of drug against the environment
(moisture, light heat)
• Improvement of flow properties of powders
• Separation of incompatible materials. Read more>>>>>>>>>>>>>>
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